VITAL Vitamin B12 Health Benefits
Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a key role in the normal functioning of the brain and nervous system and in blood formation. It is one of eight vitamins. It is usually involved in the metabolism of human cells, in particular, affects DNA synthesis and regulation, but also involves fatty acid synthesis and energy production. As the largest and most structured vitamins, it can only be produced industrially through bacterial fermentation-synthesis.
Vitamin B12 is essential for the normal functioning and health of red blood cells and nerve tissue. If not treated, vitamin B12 deficiency (also known as B12 deficiency) may lead to anemia, as well as nerve and brain damage, which may eventually become irreversible.
B12 deficiency patients may eventually develop pernicious anemia, a blood disease. Patients with pernicious anemia can not produce enough IF (intrinsic factor) in the stomach. If you need the body can absorb vitamin B12. People suffering from this blood disorder require vitamin B12 injection directly into the bloodstream, around the stomach.
Vitamin B12 Health Benefits
B12 defect symptoms
Baby grows badly / fails
Premature gray hair
Interfere with carbohydrate metabolism
Hearing loss and tinnitus
Numbness and stinging hands and feet
Pigmentation and lack of pigmentation (black and light patches on the skin)
Neuralgia, neuritis, and bursitis
Anemia, including pernicious anemia
Spinal cord degeneration
Psoriasis and other skin problems
Irrational or chronic anger
Lack of balance/gait abnormalities
Any mood disorder, including insanity
The source of vitamin B12
Mollusks (clams, oysters, mussels, etc.) 3 ounces of 84.1 micrograms
Liver, cow, 1 piece 47.9 micrograms
Trout, wild, 3 ounces of 5.4 micrograms
Salmon, 3 ounces of 4.9 micrograms
Trout, farm, 3 ounces of 4.2 micrograms
Beef sirloin, 3 ounces of 2.4 micrograms
Yogurt 1.4 micrograms
Milk, 1 cup 0.9 micrograms
Pork, marinated ham, canned, 3 ounces 0.6 micrograms
Eggs, hard pot 0.6 micrograms
Chicken breast, 1/2 chest 0.3 micrograms
Vitamin B12 recommended daily allowance
0-6 months without RDA
7-12 months without RDA
1-3 years old 0.9 micrograms
4-8 years 1.2 micrograms
9-13 years old 1.8 micrograms
14 years and above 2.4 micrograms
Pregnant 2.6 micrograms
Breastfeeding 2.8 micrograms
Low vitamin B12 in the elderly more susceptible to brain atrophy and cognitive decline.
The organization conducted a study of 121 elderly people over 65 years of age. They take blood samples to check the levels of vitamin B12 and B12-related metabolites, which also help detect defects. And their memory and other cognitive skills are also evaluated.
Fifty-two months later, the brain scanned MRI to check its size and to determine if there were signs of brain damage.
The team found that four of the five vitamins B12 deficient markers had a lower cognitive test score and a smaller total volume.
what is the reason?
Malignant anemia is caused by autoimmune diseases; a person’s own immune system attacks a large part of the body, like bacteria or viruses.
The immune system of patients with pernicious anemia produces antibodies that attack the endometrium, destroying cells that produce intrinsic factors. The intrinsic factor is the secretion of gastric mucosal material (gastric lining), which is essential for the absorption of vitamin B12 in the intestine. If the internal factors are destroyed, vitamin B12 can not be properly absorbed.
Patients with Crohn’s disease and surgical resuscitation can breathe Vitamin B12 into the bloodstream. Short bowel syndrome is a term that shortens people (less than less than half or less). Patients with short bowel syndrome usually have diarrhea, convulsions, and heartburn. Because the small intestine can not absorb enough vitamins, water, and other nutrients, so individual malnutrition is not uncommon.
If you do not eat fortified foods or certain types of yeast, then people who follow the vegan diet may suffer from B12 deficiency. Japanese and Italian scientists wrote in the Journal of Agricultural Food Chemistry that vegetarians and vegetarians are more likely to develop vitamin B12 deficiency. They explained that the body can not use plant vitamins.
According to the National Medical Library, chronic alcoholism may also be the cause of the B12 deficiency.
How to diagnose
The primary care physician will interview the patient with a physical examination to find signs of accelerating the pulse and pale or pale yellow skin.
Blood test – to determine whether the red blood cell count is low. In addition, check the appearance of red blood cells as they may have unusual shapes. Blood tests can also determine the level of B12. The doctor may also want to check the patient’s blood intrinsic factor antibody level to determine whether a person has a pernicious anemia.
Bone marrow biopsy – the purpose here is to exclude other possible causes of red blood cell abnormalities or anemia.
Scientists at the University of Gainesville, University of Florida, developed a noninvasive breathing test to diagnose vitamin B12 deficiency.
What treatment program?
Hydroxy morphine injection – this is a form of B12. Inject muscle once every two to four days. After about six injections, the patient should have a good B12 store.
In most cases, the patient will notice a significant improvement in symptoms immediately after receiving the injection.
Vegetarians who do not eat eggs and vegetarians should ensure that their B12 intake is adequate.
The annual blood tests are common to monitor the success of the treatment.
Most patients need to strengthen B12 injection every 3 months in the rest of their lives.
Vegetarians and some vegetarians – vegetarians who do not eat eggs and vegetarians should ensure that their B12 intake is adequate. There are a variety of breakfast cereals that enhance vitamin B12. Some brands of nutrient yeast are also a good source of B12. Some types of soymilk are reinforced with B12. According to Patrick J. Skerrett, executive director of Harvard Health 4, the vitamin standard contains 6 micrograms of vitamin B12, enough to meet the daily needs of ordinary people.
Test B12 defects
The first step in determining B12 deficiency is to detect B12 levels in the blood. However, many doctors believe that the blood level is the lack of unreliable indicators, even if the blood level is normal, B12 tissue levels may be quite low. They also recommend simultaneous detection of homocysteine and methylmalonic acid levels, which are two precursors of the B12-controlled metabolic response. Because homocysteine levels can be elevated by multiple conditions (folic acid deficiency, B6 deficiency, renal failure, hypothyroidism, and certain genetic defects), physicians believe that elevated levels are a reliable indicator of B12 deficiency The
Other tests included the Schilling test, where a few radioactive B12 was administered by mouth and the amount of absorption was measured. If vitamin B12 is absorbed only when the intrinsic factor is absorbed, the diagnosis of pernicious anemia can be confirmed.
Because the detection process is so complex, it is considered normal at all levels, and many physicians are likely to conclude that the only reliable way to assess the effects of micro B12 deficiency on blood, especially older patients, is to observe changes (especially Psychological changes) and empirically determine the optimal number of individual patients. Because B12 is not toxic, in addition to extremely high, the use of the high-dose treatment in an empirical manner is not dangerous.
Vitamin B12 also helps our body to absorb folic acid, which helps to release energy.
According to the American Journal of Clinical Nutrition, about 6% of people over the age of 60 are British and American vitamin B12 deficiency. Developing countries lack a more general “start from life and continue to live”.
The patient senses the symptoms and reports to the surrounding doctor or another person while others can detect a sign. An example of a symptom is a headache, rash or swelling is an example of signs.
Red blood cells
For our cells to properly reproduce, need enough vitamin B12 levels. If this production drops, vitamin B12 levels are insufficient, leading to anemia.
Vitamin deficiency is slowly progressing; they may take years to begin to affect people. Initial signs and symptoms may be subtle, but as time goes by, they become more pronounced.
For our cells to properly reproduce, need enough vitamin B12 levels. The body produces millions of red blood cells every minute. If your vitamin B12 level is low, it will cause anemia and erythrocyte count to drop.
The most common symptoms of anemia are:
Vomiting (shortness of breath)
Palpitations (irregular or serious beat feel unhappy).
B12 deficiency anemia may also be caused by a lack of intrinsic factors – pernicious anemia. The patient’s digestive system does not properly absorb B12.
Symptoms and signs of pernicious anemia may include:
Shortness of breath
Anemia may also have the following signs and symptoms:
Lips or tongue soreness
Pale yellow skin
High susceptibility to infection.
If the deficiency continues without treatment, the patient may have the following neurological symptoms and signs:
Fingers tingling or numbness
Toes tingling or numbness
General muscle weakness
Hard to walk (amazing)
How much is this?
According to the National Institutes of Health 1, how much vitamin B12 is needed every day depends on your age. The following is the average daily recommended amount of different age groups (micrograms, mcg):
Life stage recommended amount
Birth time 6 months 0.4 mcg
Infants 7 to 12 months 0.5 mcg
Children 1 to 3 years 0.9 mcg
Children 4 to 8 years old 1.2 mcg
Children 9 to 13 years old 1.8 mcg
Adolescents 14 to 18 years old 2.4 mcg
Adult 2.4 mg
Pregnant teenagers and women 2.6 mcg
Breastfeeding teenagers and women 2.8 mcg
The risk of brain contraction
Scientists at Rush University Medical Center said in a neurological report that older people with low vitamin B12 are more likely to suffer from brain atrophy and cognitive decline.
Will your brain function drop to a B12 defect?
Because B12 is so important for brain function, B12 deficiency can be manifested as numbness and hand, foot depressions, depression, and the ability to mock dementia memory and cognitive loss. Of particular importance is that older people may have a B12 deficiency because the ability to absorb vitamins decreases with age. Studies have shown that compared with the control group, B12 deficiency of the elderly B12 levels, brain shrinkage and cognitive decline less.
As a clinical dietitian and spine in the treatment of neurologists, I support my Clifton Park, a New York patient suffering from various chronic health problems. B12 lack of chronic health problems or brain function is not uncommon. I see Guilderland, Loudonville, Delmar, Colonie and other capital of the patient. When patients complain about chronic health, we use clinical nutrition, diet strategies and other tools to manage the condition. Solving B12 defects is an important part of the overall approach.
Are you anemia B12?
Other common symptoms of B12 deficiency are anemia symptoms, including fatigue, lethargy, and weakness. Patients with type B12 anemia found an autoimmune disease known as harmful anemia that could inhibit the absorption of B12. In this case, managing autoimmune diseases is important, supplementing B12 by sublingual or injections.
B12 deficiency is also associated with increased risk of cardiovascular disease, autism, autoimmune diseases, and infertility.
B12 deficiency is often due to poor absorption
Then the lack of B12? For many people, this is not because of diets and poor nutrition.
Today, many people suffer from food inflammation, chronic stress and food intolerance such as gluten damage. B12 and other nutrients difficult to enter through the inflammation and intestinal intima into the blood.
Other factors that may cause B12 deficiency include gastric acid (common in the elderly), the use of antacids and antacids, the use of metformin and other prescription drugs, alcoholism and weight loss surgery.
In the absence of B12, should always be treated to restore and restore intestinal health.
In the center of the capital district, we can help Guilderland, Loudonville, Delmar, Colonie and other parts of the capital to solve the B12 deficiencies and better support their condition.
Vitamin B12 lacks the risk of vegetarians and vegetarians
B12 The risk of a lack of diet is vegetarian, vegetarian B12 is found only in animal food. B12 Natural plant sources such as spirulina, algae, seaweed or grass are poorly absorbed, which can lead to laboratory results with normal B12 errors. This person should especially add B12.
In addition, although intestinal bacteria can synthesize B12, but this requires healthy bowel function and flora, most of the B12 synthesis is absorbed downstream of the small intestine.
B12 is an indispensable vitamin with a systemic effect. Need to develop and maintain a healthy nervous system, produce DNA and form red blood cells.
Severe B12 deficiency can lead to anemia, which can be detected by ordinary blood tests. However, the symptoms of B12 deficiency are less pronounced and may include mood disorders such as muscle weakness, fatigue, tremor, gait instability, incontinence, hypotension, depression and lack of memory.
The labs are different in what they think is normal, but most authorities say that defects occur when adult B12 levels are lower than 250 picograms per milliliter of serum. Like all B vitamins, B12 is water-soluble, but the body stores extra B12 in the liver and other tissues. Even if the diet is less than a period of time, serum deficiency may not occur for years.
If the B12’s storage is low, at the beginning, infants and young children develop less than a year, or even faster.
B12 recommended dietary intake of different: 14 years and over the crowd 2.4 micrograms per day, 2.6 micrograms of pregnant women, lactating women 2.8 micrograms. Limiting the absorption of B12, B12 is readily available from a balanced diet containing animal protein.
In its natural form, B12 is only present in animal food, especially in the liver (83 micrograms to 3.5 ounces). Good food sources include other red meat, turkey, fish, and shellfish. Several vitamins are found in dairy products, eggs, and chicken.
There is a risky person
Natural plant sources are not significant in B12, poor vitamin absorption. Many strict vegetarians and all vegetarians and their breastfeeding babies must consume supplements or fortify the breakfast cereals to get enough volume.
Some creatures, such as bacterial spirulina and some algae, contain false B12 that can not be used by the body but may lead to the erroneous reading of normal B12 levels in blood tests. On the contrary, seaweed and barley grass are not a reliable source of B12.
In animal food, B12 binds to the protein and must be released by the acid and the absorbed enzyme. Thus, chronic agents such as Prilosec, Prevacid and Nexium, and other chronic drugs such as Pepcid and Tagamet have a risk of developing a B12 deficiency, which usually requires daily B12 supplements.
The level of gastric acid decreased with age. Up to 30% of older people may lack enough stomach acid to absorb enough B12 from natural sources. Therefore, for people over 50 years of age, it is recommended that regular intake of food or supplement 25 to 100 micrograms of B12 per day.
Synthetic B12 found in supplements and fortified foods does not depend on the absorption of gastric acid. But whether it is natural or synthetic, only some of the consumption of B12 into the body. The treatment of correcting B12 deficiency usually involves a greater dose than the actual dose required by the body.
Free B12 from natural and synthetic sources must be combined with substances known as stomach internal factors to be absorbed through the intestine. People with autoimmune diseases known as pernicious anemia, lack of this factor; the resulting vitamin deficiency is usually treated with an injection of B12.
Although most physicians have quickly recommended injections to correct the B12 deficiency, there is considerable evidence that sublingual (sublingual) tablets or skin patches of B12 may be injected at a sufficiently large dose, even for pernicious anemia.
In most cases, it is advisable to add 2000 micrograms a day for about a month and then drop to 1000 micrograms per day and then drop to 1000 micrograms per week. Sublingual B12 or B12 patches, and even B12 lollipops can help people who need to replenish but can not swallow pills.
Other people who found B12 deficiency included those who had severe drinkers (alcohol-reduced B12 uptake), who experienced weight loss or ulcers, and Glucophage et al. Took aminosalicylic acid (inflammatory bowel disease or tuberculosis) or diabetes medicine The Brand sales). Patients taking phenytoin, phenobarbital or edema are also at risk.
If normal B12 levels are not maintained, high doses of folic acid can mask B12 deficiency and cause permanent nerve damage. Potassium supplement some B12 absorbed people.
Although B12 deficiency can increase the blood levels of amino a diacid homocysteine, but the risk factor use and stroke, B12 supplements do not reduce cardiovascular risk.